Observations is a collaborative coffee table book with photography by Richard Avedon, commentary by Truman Capote and design by Alexey Brodovitch. It features a slipcase with color, all-capitalized lettering; the book itself is further housed in a clear acetate/glassine slip cover and is printed with the same bold design as the slipcase in black-and-white.

Paired receptors are pairs or clusters of receptor proteins that bind to extracellular ligands but have opposing activating and inhibitory signaling effects. Traditionally, paired receptors are defined as homologous pairs with similar extracellular domains and different cytoplasmic regions, whose genes are located together in the genome as part of the same gene cluster and which evolved through gene duplication.

<hardware> (Obsolete, or "bit-shift keyboard") A non-standard keyboard layout that seems to have originated with the Teletype ASR-33 and remained common for several years on early computer equipment. The ASR-33 was a mechanical device (see EOU), so the only way to generate the character codes from keystrokes was by some physical linkage. The design of the ASR-33 assigned each character key a basic pattern that could be modified by flipping bits if the SHIFT or the CTRL key was pressed. In order to avoid making the thing more of a Rube Goldberg kluge than it already was, the design had to group characters that shared the same basic bit pattern on one key. Looking at the ASCII chart, we find: high low bits bits 0000 0001 0010 0011 0100 0101 0110 0111 1000 1001 010 ! " # $ % & ' ( ) 011 0 1 2 3 4 5 6 7 8 9 This is why the characters !"#$%&'() appear where they do on a Teletype (thankfully, they didn't use shift-0 for space). This was *not* the weirdest variant of the QWERTY layout widely seen, by the way; that prize should probably go to one of several (differing) arrangements on IBM's even clunkier 026 and 029 card punches. When electronic terminals became popular, in the early 1970s, there was no agreement in the industry over how the keyboards should be laid out. Some vendors opted to emulate the Teletype keyboard, while others used the flexibility of electronic circuitry to make their product look like an office typewriter. These alternatives became known as "bit-paired" and "typewriter-paired" keyboards. To a hacker, the bit-paired keyboard seemed far more logical - and because most hackers in those days had never learned to touch-type, there was little pressure from the pioneering users to adapt keyboards to the typewriter standard. The doom of the bit-paired keyboard was the large-scale introduction of the computer terminal into the normal office environment, where out-and-out technophobes were expected to use the equipment. The "typewriter-paired" standard became universal, "bit-paired" hardware was quickly junked or relegated to dusty corners, and both terms passed into disuse. [Jargon File] (1995-02-20)